Related Experiment Video
Updated: May 12, 2025

Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
Elbow osteomyelitis by Candida tropicalis in acute lymphoblastic leukemia. A case report
S Kohan-Fortuna-Figueira1, M Latorre1, P Dardanelli1
1Scoliosis and Pediatric Orthopedic Center, «Carlos Ottolenghi» Orthopedic and Traumatology Institute, Hospital Italiano de Buenos Aires. Buenos Aires, Argentina.
Introduction:
musculoskeletal involvement of the extremities is common in pediatric patients with acute lymphoblastic leukemia. The insidious and oligosymptomatic presentation of several musculoskeletal conditions in these patients often leads to different diagnostic suspicions, which may delay appropriate management of the pathology. Non-albicans Candida osteoarticular infections are a rare entity that may affect immunodeficient patients. We describe a case of osteoarticular infection caused by an opportunistic fungus in a pediatric patient with acute lymphoblastic leukemia during the second week of rest post-consolidation block.
Case Presentation:
we present a case of a 4-year-old girl diagnosed with B-cell acute lymphoblastic leukemia that developed an elbow infection by Candida tropicalis. Two surgical debridements of the elbow, combined with the administration of antifungals, were required to control the infection. She fully recovered at six months postoperatively and remains without osteoarticular sequelae at three years of follow up.
Conclusion:
C. tropicalis infection should be included in the differential diagnosis of osteoarticular complications in immunocompromised patients with acute lymphoblastic leukemia (ALL). Prompt diagnosis and treatment are essential to avoid osteoarticular sequelae.
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...

