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Unravelling T Cell Immunity in CAR-T Therapy: Implications for Influenza Vaccination

Adam G Stewart1, Roy F Chemaly2

  • 1Transplant and Immunocompromised Host Infectious Diseases, Infectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Royal Brisbane and Women's Hospital Campus, Brisbane, Australia.

Transplantation and Cellular Therapy
|May 7, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
chimeric antigen receptorinfluenzavaccination

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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