Related Experiment Video
Updated: Jul 1, 2026
07:56
Genome Editing in Mammalian Cell Lines using CRISPR-Cas
Published on: April 11, 2019
21.4K
Towards Precision Geromedicine in Singapore
Jonas John Posko Amalaraj1, Louis Island1, Jane Yu Ying Ong1
1NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, 117456, Singapore.
Geroscience
|May 7, 2025
Summary
Singapore is advancing Precision Geromedicine to combat rising age-related diseases (ARDs). The nation is focusing on healthy ageing initiatives and integrating gerodiagnostics and gerotherapeutics into clinical practice.
Area of Science:
- Geroscience
- Precision Geromedicine
- Public Health
Background:
- Ageing is a modifiable process, driving advancements in geroscience.
- Age-related diseases (ARDs) represent a significant health burden, projected to increase as Singapore becomes a "super-aged" nation by 2030.
- Singapore's healthcare system is adapting to focus on healthy ageing, exemplified by the Healthier SG initiative.
Purpose of the Study:
- To explore the emergence and potential of Precision Geromedicine.
- To highlight Singapore's strategic response to the growing challenge of ARDs.
- To position Singapore as a potential global model for addressing ARDs.
Main Methods:
- Review of advancements in geroscience and the development of Precision Geromedicine.
- Analysis of Singapore's healthcare initiatives and investments in geroscience.
- Assessment of Singapore's healthcare system, digital infrastructure, and socio-political stability.
Main Results:
- Precision Geromedicine aims to optimize healthspan by targeting ageing processes.
- Singapore is actively reshaping its healthcare system towards proactive health management and healthy ageing.
- Investment in geroscience is laying the groundwork for integrating gerodiagnostics and gerotherapeutics into clinical practice.
Conclusions:
- Singapore's proactive approach positions it to address ARDs effectively.
- The nation's infrastructure and stability provide a strong foundation for implementing Precision Geromedicine.
- Singapore has the potential to become a leading model for healthy ageing and ARD management globally.
Related Concept Videos
02:50Combination Therapies and Personalized Medicine
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
02:50Combination Therapies and Personalized Medicine
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
01:29Pharmacogenomics: Identification of New Drug Targets
Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
01:29Microorganisms in Medicine and Therapeutics
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.