Related Experiment Video
Updated: May 12, 2025

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
Bladder Pain Syndrome With Repeated Bladder Hydrodistention-A Case of Functional Somatic Syndrome Considered in
Naoki Wada1, Tsubasa Hatakeyama1, Taichiro Ishimaru1
1Department of Renal and Urologic Surgery Asahikawa Medical University Asahikawa Japan.
Introduction:
We present a patient with bladder pain syndrome (BPS) who underwent repeated bladder hydrodistentions.
Case Presentation:
A female patient visited our department because of refractory bladder pain. She was diagnosed with BPS; she had only mucosal bleeding after distention. Her bladder pain improved after hydrodistention; however, the symptoms flared up within a few months. She also consulted with the palliative care department and was diagnosed with chronic pain associated with alexithymia. Various drugs were administered; however, none were effective or continued because of side effects. It was also challenging for her to embrace introspective counseling. Ultimately, along with her strong desire, the hydrodistention continued every few months. Her bladder capacity was approximately 200 mL.
Conclusion:
BPS with uncontrolled bladder pain may be a functional somatic syndrome associated with alexithymia, and interventions such as psychosomatic medicine could be necessary from the early stage.
Related Concept Videos
Disorders of the Urinary System
Urinary tract infections (UTIs) are one of the most common urinary system disorders. They are caused by bacteria that enter the urethra and can spread to the bladder resulting in cystitis. Pyelonephritis is the result of a UTI that has ascended to the level of the...
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...

