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Updated: May 12, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
Published on: November 2, 2018
Crystal structure and Hirshfeld surface analysis of ketorolac tromethamine
Anna M Shaposhnyk1, Vitalii V Rudiuk2, Vyacheslav N Baumer1
1Institute of Functional Materials Chemistry SSI 'Institute for Single Crystals' NAS of Ukraine 60 Nauky Ave Kharkiv 61001 Ukraine.
Abstract:
Ketorolac tromethamine or 1,3-dihy-droxy-2-(hy-droxy-meth-yl)propan-2-am-inium 5-benzoyl-2,3-di-hydro-1H-pyrrolizine-1-carboxyl-ate, C15H12NO3 +·C4H12NO3 -, was studied by single-crystal and powder X-ray diffraction methods. One cation and one anion are present in the asymmetric unit. In the crystal, N-H⋯O and O-H⋯O hy-dro-gen bonds link the cation and anion. All the hy-dro-gen-bond inter-actions result in the formation of a di-periodic layer in the (100) crystallographic plane.
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