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Congenitally corrected transposition of the great arteries: one disease, diverse manifestations-a case series

Maria Luisa Benesch Vidal1, Han Ki Park2, Kouichi Toda3

  • 1Department of Cardiology, University Heart and Vascular Centre Hamburg, Martinistr. 52, 20251 Hamburg, Germany.

European Heart Journal. Case Reports
|May 8, 2025
PubMed

Insights

Congenitally corrected transposition of the great arteries (ccTGA) presents diverse challenges. Multimodality imaging is crucial for diagnosing and managing this rare heart defect across a patient's lifespan.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Cardiovascular Imaging

Background:

  • Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect.
  • ccTGA exhibits heterogeneous clinical manifestations, posing lifelong diagnostic and management challenges.

Observation:

  • Four patients with ccTGA presented with varied clinical scenarios: sudden cardiac arrest, progressive heart failure, postpartum heart failure, and NSTEMI.
  • Management of pregnancy in patients with a systemic right ventricle (sRV) and acquired heart disease development present unique challenges.

Findings:

  • Multimodality imaging is essential for accurate diagnosis and effective treatment strategies in ccTGA.
  • Long-term sequelae include arrhythmias and heart failure, requiring careful management.

Implications:

  • This case series underscores the critical role of advanced imaging in ccTGA patient care.
  • Comprehensive, lifelong management strategies are necessary for individuals with ccTGA, addressing diverse complications and specific life stages.
Abstract

Keywords:
Cardio-obstetric managementCase seriesCongenitally corrected transposition of the great arteriesCoronary artery diseaseHeart failureVentricular assist device

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