Normothermic machine perfusion in liver transplantation: a bibliometric analysis of the top 100 most cited articles
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Updated: May 12, 2025

Ex Situ Normothermic Machine Perfusion of Donor Livers
Published on: May 26, 2015
Hiba Thasleem1, Muhammad Ahmad Nadeem2, Hamza Ashraf3
1Fatima Jinnah Medical University, Lahore, Pakistan.
Background:
Normothermic machine perfusion (NMP) has increased substantially in the recent decade, being a vital tool in further organ preservation and reducing ischemia-reperfusion injury. The purpose of this study was to objectively conduct a bibliometric analysis of the top 100 cited articles to understand the evolution of NMP in liver transplantation.
Methods:
Scopus was selected as our primary database. We explored the database to extract relevant articles, which were then ranked numerically by the number of citations. A list of the top 100 articles was created in descending order, and each article was further analyzed to identify trends and characteristics. A list of the top 10 review articles was also prepared.
Results:
The top 100 studies were cited a total of 6136 times from 2013 and 2023, with the most cited articles published in 2018. The total number of citations per article ranged from 7 to 787, with a median of 397 citations. The articles originated from 13 different countries, with the United Kingdom having the most articles (n = 26), followed by the Netherlands (n = 17) and the United States (n = 17). Liver Transplantation (n = 21), Transplantation (n = 10), American Journal of Transplantation (n = 10), and Annals of Surgery (n = 6) contributed to nearly half of the articles.
Conclusion:
Research on NMP is rapidly growing and encompasses a variety of countries and institutions. Our analysis provides insight into the evolution of normothermic machine perfusion in liver transplantation, with the hope that this article may serve as a reference to aid healthcare professionals in efficiently assessing consensus, trends, and needs within the field.

