Risk factors of mortality among heart failure patients in Jordan: the Jordanian Heart Failure Registry (JoHFR)

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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

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Kais Al-Balbissi1, Akram Al-Saleh1, Hanna Al-Makhamreh1

  • 1Cardiology Section, Internal Medicine Department, Jordan University Hospital, Amman, Jordan.

Annals of Medicine and Surgery (2012)
|May 8, 2025
PubMed

Insights

This heart failure registry in Jordan identified key mortality risk factors. Smoking, family history of heart disease, insulin use, hyponatremia, and larger left ventricular diameter predict worse outcomes for heart failure patients.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Heart failure represents a significant global health burden.
  • Limited data exists on heart failure in the Middle East, with only two prior registries.
  • This study addresses the need for regional data on heart failure management and outcomes.

Purpose of the Study:

  • To conduct a prospective, observational, multicenter national registry in Jordan.
  • To investigate the follow-up results and identify mortality predictors in patients with acute and chronic heart failure.
  • To establish a baseline for future heart failure research and interventions in the region.

Main Methods:

  • A prospective observational multicenter national registry was conducted across 21 health institutes in Jordan.
  • Inclusion criteria involved patients visiting cardiology clinics or admitted with acute decompensated heart failure.
  • The primary outcome measured was 30-day mortality.

Main Results:

  • A total of 2128 patients were enrolled, with 204 deaths during follow-up.
  • Multivariate analysis revealed significant associations between mortality and smoking (OR=3.214), positive family history of premature coronary artery disease (OR=2.686), insulin use (OR=2.300), hyponatremia (OR=7.058), and increased left ventricular diameter (OR=1.009).
  • These factors were identified as significant predictors of increased mortality risk.

Conclusions:

  • Key factors associated with heart failure patient mortality include smoking, a positive family history of premature coronary artery disease, insulin use, hyponatremia at presentation, and increased left ventricular diameter.
  • Physicians should actively monitor these identified risk factors to stratify patients and manage those at higher risk of adverse outcomes.
  • This registry provides valuable insights for improving heart failure care protocols in Jordan and potentially other similar healthcare settings.
Abstract

Keywords:
Jordanheart failuremortalityregistry

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