Related Experiment Video
Updated: May 12, 2025

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
Characteristics of men using non-prescription medicines to treat their lower urinary tract symptoms
Martin C Michel1, Kurt Miller2, Tim Schneider3
1Department of Pharmacology, University Medical Center, Johannes Gutenberg University, Mainz, Germany. marmiche@uni-mainz.de.
Purpose:
Many men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) opt for self-management with non-prescription treatments. We wished to better characterize these men and understand their motivation and experience.
Methods:
We conducted an anonymous survey among 477 users of non-prescription treatments for LUTS.
Results:
Participating men had a mean age (64.3 ± 7.8 years) and IPSS (17.7 ± 7.9 points) comparable to users of prescription medicines in non-interventional studies, indicating that they were not primarily motivated by mild symptom intensity. They had realistic expectations on efficacy and tolerability. While reasons for preference for a non-prescription treatment varied, 40.0% stated a wish to avoid 'chemical' and, vice-versa, to use 'natural' treatments. The choice of a specific treatment was largely driven by prior experience, but recommendations from a physician or the pharmacy as well as advertisements also played a role. About two thirds of participants reported to be repeat users and purchasing the same product each time. However, less than a quarter of participants appear to use the non-prescription treatment continuously.
Conclusions:
Men self-managing their LUTS/BPH are similar to those using prescription drugs based on age and symptom severity. Their main reasons to prefer non-prescription medicines relate to the wish to avoid 'chemical' and the preference for 'natural' treatments. Most of them are repeat users of the same product but use it only intermittently.
Related Concept Videos
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Cholinergic Antagonists: Pharmacokinetics

