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Non-proliferative diabetic retinopathy detection using Rosmarus Quagga optimized explainable generative meta learning
Ajita Arvind Mahapadi1, Vishal Shirsath2, Ajitkumar Pundge2
1School of Engineering, Ajeenkya D Y Patil University, Lohegaon, Pune, Maharashtra, 412105, India. ajita.mahapadi@adypu.edu.in.
International Ophthalmology
|May 8, 2025
Summary
This study introduces a novel Rosmarus Quagga optimized Explainable generative Meta learning based Deep Convolutional Neural Network (RQ-EGMCN) for diagnosing Non-Proliferative Diabetic Retinopathy (NPDR). The model achieves high accuracy in detecting diabetic retinopathy from retinal images.
Area of Science:
- Ophthalmology
- Medical Imaging
- Artificial Intelligence
Background:
- Non-Proliferative Diabetic Retinopathy (NPDR) is an early-stage complication of diabetes affecting retinal blood vessels.
- Existing diagnostic models struggle with lesion heterogeneity (size, shape, distribution).
- Accurate and early NPDR diagnosis is crucial for diabetes management.
Purpose of the Study:
- To develop and validate a novel model for effective diagnosis of severe diabetic retinopathy (DR) with lesion recognition.
- To address challenges in existing NPDR detection models.
- To improve the accuracy and interpretability of DR diagnosis using retinal images.
Main Methods:
- Proposed a Rosmarus Quagga optimized Explainable generative Meta learning based Deep Convolutional Neural Network (RQ-EGMCN).
- Integrated adaptive foraging and leader-based feeding strategies for enhanced detection accuracy.
- Employed explainable CNNs with attention/saliency maps for interpretability.
- Utilized generative components for realistic retinal image synthesis and meta-learning for accelerated generalization.
Main Results:
- The RQ-EGMCN model achieved high performance on a diabetic retinopathy detection dataset.
- Maximum accuracy of 95.47%, precision of 95.34%, and recall of 95.24% were recorded.
- The model demonstrated improved diagnostic accuracy, reduced computational complexity, and enhanced versatility.
Conclusions:
- The proposed RQ-EGMCN model offers an effective solution for NPDR diagnosis.
- Explainable AI components enhance decision-making transparency in DR detection.
- The model shows significant potential for clinical application in diabetic eye care.

