Antibiotic sensitivity of gonococci in South Australia, 1974 to 1975

Routine testing of gonococci isolated from patients attending the Venereal Diseases Control Centre in Adelaide during the year July, 1974 to June, 1975, with a plate dilution method, showed that 93-8% of the 947 infecting strains were relatively sensitive to penicillin at a minimum inhibitory concentration (MIC) of 0-12 units/ml or less, and that 90% of the 648 strains tested were relatively sensitive to tetracycline at an MIC of 1-0 mug/ml or less. A small proportion only of isolates were relatively insensitive to penicillin and/or tetracycline. The routine treatment schedules which were used at the Centre proved adequate for infections over the whole range of sensitivities encountered. A significant proportion of the less sensitive strains were isolated from people infected in South-East Asia, most of whom had been inadequately treated there.