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Stakeholders' Perspectives on Medication Adherence Enhancing Interventions.
Bijan J Borah1, Lisa J Pieretti2, Alan J Balch3
1Mayo Clinic College of Medicine and Science and the Kern Center for the Science of Health Care Delivery, Rochester, MN, USA.
Summary
Medication nonadherence affects 50% of patients, leading to adverse events and high costs. A systematic literature review found that while clinical outcomes are measured, economic and patient-reported outcomes need more focus for adherence interventions.
Area of Science:
- Health Economics
- Patient Adherence Research
- Healthcare Management
Background:
- Medication nonadherence presents a significant healthcare challenge with approximately 50% prevalence, leading to avoidable adverse events and substantial annual costs per person.
- The ISPOR Medication Adherence and Persistence Special Interest Group's 2023 systematic literature review (SLR) aimed to evaluate measures for assessing medication adherence enhancing interventions (MAEIs).
Purpose of the Study:
- To supplement SLR findings by presenting stakeholder perspectives on assessing MAEIs.
- To identify gaps in outcome measurement for MAEIs and propose future research directions.
Main Methods:
- Systematic literature review (SLR) conducted in 2023.
- Analysis of stakeholder perspectives (patients, manufacturers, providers, health technology assessment agencies, payers).
Main Results:
- The SLR revealed frequent measurement of medication adherence and clinical outcomes, but underexplored economic and patient-reported outcomes.
- Stakeholders emphasize the need for MAEIs to demonstrate improved clinical outcomes, quality of life, and cost savings.
- The SLR highlighted a need for consensus-based criteria for assessing MAEIs.
Conclusions:
- MAEIs require a comprehensive approach, incorporating personalized strategies based on socioeconomic factors and social needs.
- Future research should quantify MAEI implementation costs and stakeholder cost-bearing mechanisms for widespread adoption.
- Integrating artificial intelligence and patient-centered approaches is crucial for developing effective, personalized adherence strategies.
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