The Guidance of Head-Neck-Aorta CT Angiography in Acute Type A Aortic Dissection Patients
Hongliang Zhao1, Chengxiang Li2, Jian Xu1
1Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Insights
Preoperative extended head-neck-aorta CTA in acute type A aortic dissection (ATAAD) surgery improved neurological outcomes. This imaging approach identified critical carotid artery issues, leading to modified surgical strategies and reduced permanent neurological deficits.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Radiology
Background:
- The diagnostic value of preoperative craniocervical artery imaging for acute type A aortic dissection (ATAAD) surgical repair remains unclear.
- Optimal surgical decision-making in ATAAD may benefit from detailed anatomical information of the head and neck vasculature.
Purpose of the Study:
- To investigate the clinical significance of preoperative extended head-neck-aorta computed tomography angiography (CTA) in patients with ATAAD.
- To evaluate the impact of extended CTA on neurological outcomes following ATAAD surgical repair.
Main Methods:
- A retrospective analysis of ATAAD patients undergoing surgical repair was conducted.
- Patients were divided into conventional aortic CTA (215) and extended CTA (220) groups.
- A 1:1 propensity score matching analysis created 154 pairs to compare outcomes, with the primary endpoint being postoperative neurological deficits.
Main Results:
- The extended CTA group revealed significant common carotid artery stenosis or occlusion in 35% of asymptomatic patients.
- The extended CTA group more frequently utilized common carotid artery reconstruction and bilateral antegrade selective cerebral perfusion.
- In the matched cohort, extended CTA was significantly associated with fewer postoperative permanent neurological deficits (aOR: 0.186; P = 0.004).
Conclusions:
- Extended head-neck-aorta CTA provides crucial preoperative anatomical detail for ATAAD surgical planning.
- This enhanced imaging protocol facilitates modified surgical strategies, potentially improving neurological outcomes in ATAAD patients.
Background:
The benefit of preoperative craniocervical artery imaging has not been elucidated for decision-making during the surgical repair of acute type A aortic dissection (ATAAD).
Objectives:
The purpose of this study was to explore the clinical implication of a preoperative extended head-neck-aorta computed tomography angiography (CTA) among ATAAD patients.
Methods:
ATAAD patients undergoing surgical repair were retrospectively enrolled. Preoperatively, 215 patients underwent aortic CTA (conventional group) and 220 underwent extended CTA (extended group). In the extended group, the surgical team was informed of assessment of craniocervical arteries before the operation. The primary endpoint was postoperative transient neurological deficit and permanent neurological deficit. A 1:1 propensity score matching analysis was performed to account for baseline differences between groups, resulting in 154 pairs.
Results:
In the extended group, 135 patients were free of preoperative neurological symptoms, but 35 (25.9%) presented with severely stenosed or occluded common carotid artery. Common carotid artery reconstruction and cannulation combined with femoral artery cannulation (24.1% vs 5.1%; P < 0.001) and bilateral antegrade selective cerebral perfusion during hypothermic circulatory arrest (56.4% vs 19.1%; P < 0.001) were more adopted in the extended group. In the matched cohort, the extended CTA was significantly associated with fewer postoperative permanent neurological deficit (adjusted OR: 0.186; 95% CI: 0.059-0.587; P = 0.004) after adjustment with logistic regression.
Conclusions:
The extended head-neck-aorta CTA protocol provided additional anatomical clarity preoperatively for modified surgical strategies and may subsequently improved the neurological outcomes of ATAAD.
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