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Updated: May 14, 2025

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
Predicting Mesothelioma Using Artificial Intelligence: A Scoping Review of Common Models and Applications
Malihe Ram1, Mohammad Reza Afrash2, Khadijeh Moulaei3
1Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran.
Artificial intelligence (AI) shows promise for predicting mesothelioma, a lung cancer linked to asbestos. Machine learning models like support vector machines and random forests achieve high accuracy in diagnosis and staging, improving patient outcomes.
Area of Science:
- Oncology
- Medical Informatics
- Data Science
Background:
- Mesothelioma is a serious lung cancer often caused by asbestos exposure.
- Early diagnosis is critical for improving patient survival rates.
- Artificial intelligence (AI) presents a promising avenue for enhancing mesothelioma diagnosis and staging.
Purpose of the Study:
- To review recent research on AI applications for mesothelioma prediction and management.
- To identify the most effective AI models and their applications in mesothelioma research.
Main Methods:
- A comprehensive literature search was conducted across PubMed, Scopus, and Web of Science databases until April 24, 2023.
- Nineteen relevant articles were selected after initial screening and duplicate removal.
- Data extraction and synthesis were performed using standardized forms and presented in figures and tables.
Main Results:
- AI applications in mesothelioma research primarily focus on tumor diagnosis and classification (73.69%).
- Other applications include prevention, prognosis (21.05%), and tumor volumetric measurement (5.26%).
- Prominent AI models like Support Vector Machines (SVM), Decision Trees (DT), and Random Forests (RF) demonstrated high accuracies (78.3%–99.97%).
Conclusions:
- AI, especially machine learning models (NN, DT, RF, SVM), shows significant potential in predicting and managing mesothelioma.
- These AI tools can enhance early detection and improve patient outcomes for mesothelioma.
- Further research into AI applications can refine diagnostic and prognostic capabilities for this disease.
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