Evaluation of Dynamic Intraocular Lens Movement Using Anterior Segment Optical Coherence Tomography Movie Analysis

Area of Science:

• Ophthalmology
• Medical Imaging
• Biomedical Engineering

Background:

• Intraocular lens (IOL) stability is crucial for visual outcomes after cataract surgery.
• Conventional methods for assessing IOL position rely on static measurements, which may not capture dynamic changes during eye movements.

Purpose of the Study:

• To introduce and validate a quantitative method for assessing dynamic intraocular lens (IOL) positioning using anterior segment optical coherence tomography (AS-OCT).
• To compare dynamic IOL and iris movement with static IOL tilt and decentration.

Main Methods:

• Retrospective analysis of 13 eyes with in-the-bag IOL fixation.
• AS-OCT imaging during horizontal eye movements to quantify dynamic IOL and iris movement angles.
• Comparison of dynamic measurements with conventional static IOL tilt and decentration.

Main Results:

• Static IOL tilt averaged 4.1° ± 1.3° and decentration 0.17 ± 0.10 mm.
• Dynamic analysis revealed IOL movement angles of 2.6° ± 2.1° and iris movement angles of 4.1° ± 3.4°.
• No correlation between dynamic IOL movement and static parameters, but a strong positive correlation between dynamic IOL and iris movement (R = 0.83, P < .05).

Conclusions:

• Significant dynamic oscillations in IOL positioning were detected despite normal static measurements.
• Dynamic assessment is important for evaluating IOL stability during daily activities.
• Dynamic evaluation of IOL position holds potential value in routine clinical practice.