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Updated: May 13, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Massive Thymic Hyperplasia in Graves Disease
Christopher Chan1,2, Simon Ryder1, Dianna Luong1,3
1Logan Endocrine and Diabetes Service, Logan Hospital, Metro South Health, Meadowbrook, Brisbane, QLD 4131, Australia.
Abstract:
Thymic hyperplasia (TH) is a rare but established complication of Graves disease (GD). It is a benign phenomenon that regresses with appropriate treatment of GD. We report the case of a Burmese refugee with newly diagnosed GD, who had an incidental thymic mass measuring 70 mm × 21 mm × 121 mm. The size of the mass exceeded typical reports in the literature but was not accompanied by a substantial thyrotoxicosis. As the mass receded with antithyroid medication, a presumptive diagnosis of TH was ultimately made. Recognition of this association is vital to prevent unnecessary biopsy and surgical intervention.
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