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Adverse Events Should Not Be Surprising in Psychedelic Research
Rebecca Ehrenkranz1, Manish Agrawal2, Sandeep M Nayak1
1Center for Psychedelic and Conciousness Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Psychedelic therapies offer benefits but also carry risks. A balanced view, grounded in clinical evidence, is crucial for public and scientific understanding of psychedelic treatments.
Area of Science:
- Psychiatry
- Neuroscience
- Pharmacology
Background:
- Psychedelics show therapeutic potential for mental health conditions.
- Current public discourse often emphasizes benefits over risks.
- A balanced perspective on psychedelic risks and benefits is needed.
Purpose of the Study:
- To advocate for a more balanced scientific and public discourse on psychedelic therapies.
- To highlight the necessity of acknowledging both risks and benefits.
- To emphasize evidence-based communication regarding psychedelic treatments.
Main Methods:
- Review of existing research on psychedelic risks and benefits.
- Analysis of public discourse trends in psychedelic science.
- Consideration of clinical trial data and participant reports.
Main Results:
- Adverse events from psychedelics range from mild to severe.
- Increased study and relaxed eligibility criteria may increase adverse event incidence.
- Quantifying and communicating the risk/benefit profile is essential.
Conclusions:
- Balanced attention to psychedelic risks and benefits is vital for the scientific community and public.
- Public education on the nature and existence of psychedelic risks is necessary.
- Effective communication of the psychedelic risk/benefit profile is increasingly important.
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