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Updated: May 12, 2025

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Possible Capecitabine-Induced Coronary Vasospasm and Myocardial Infarction
Deepa Soodi1, Vinod Kumar Reddy Cirra2, Guruprasad D Naik3,1
1Cardiology, Marshfield Clinic Health System, Marshfield, USA.
Abstract:
Capecitabine is a 5-fluorouracil precursor, approved for breast and colorectal cancer. We report a case of capecitabine-induced coronary vasospasm. A 77-year-old woman with breast cancer receiving capecitabine presented with chest pain, and an electrocardiogram demonstrated acute anterior-lateral myocardial infarction. Coronary angiography demonstrated normal coronary arteries. Discontinuation of capecitabine resolved symptoms. Failing to identify the cardiotoxicity associated with capecitabine could have had serious consequences.
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