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High-grade appendiceal mucinous neoplasms in children: a case report
Hongli Wang1, Jin Zhang2, Xiwei Hao1
1Department of Pediatric Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Frontiers in Pediatrics
|May 9, 2025
Summary
Appendiceal mucinous neoplasms (AMNs) are rare and often misdiagnosed. Early detection and treatment, as shown in this pediatric case, are vital to prevent progression to peritoneal pseudomyxoma.
Area of Science:
- Gastroenterology
- Oncology
- Pediatric Surgery
Background:
- Appendiceal mucinous neoplasms (AMNs) are rare, characterized by mucus accumulation in the appendix.
- AMNs are frequently misdiagnosed as appendicitis, potentially progressing to peritoneal pseudomyxoma (PP).
Observation:
- A 13-year-old male presented with suspected acute appendicitis.
- Laparoscopic appendectomy revealed high-grade appendiceal mucinous neoplasm (HAMN) with focal muscular invasion.
Findings:
- The patient underwent successful laparoscopic ileocecal resection, hyperthermic intraperitoneal chemotherapy (HIPEC), and molecular targeted therapy.
- Multidisciplinary discussion confirmed the treatment plan's appropriateness, leading to a favorable outcome.
Implications:
- This case underscores the importance of considering appendiceal tumors in pediatric diagnoses.
- Timely recognition and appropriate surgical management are crucial for preventing advanced abdominal pathology.
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