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Updated: May 13, 2025

Visualizing Single-molecule DNA Replication with Fluorescence Microscopy
Published on: October 9, 2009
The replication rate of Anaplasma marginale is temperature-mediated in ticks
Popy Devnath1, Susan M Noh2, Shelby M Jarvis2
1Washington State University, Pullman, Washington, United States.
Abstract:
Anaplasma marginale , the cause of bovine anaplasmosis, a serious production-limiting disease of cattle found worldwide, is biologically transmitted by adult male Dermacentor spp. ticks in the United States. We tested the impact of 9 temperatures on infected D. andersoni and found that the replication of A. marginale in tick midguts and salivary glands is temperature dependent. There were higher bacterial levels between 32°C and 37°C than between 4°C to 26°C. We observed 100% mortality in ticks at 42°C. Future research should explore the mechanisms of temperature-dependent replication in A. marginale and possible links to transmission rates under climate change.
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