Related Experiment Video
Updated: Apr 29, 2026

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Studying the Supramolecular Organization of Photosynthetic Membranes within Freeze-fractured Leaf Tissues by Cryo-scanning Electron Microscopy
Published on: June 23, 2016
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Restoration of a Stuck Leaflet.
Elisa Tomarelli1, Gianluca Di Pietro1, Gennaro Sardella1
1Department of Clinical, Internal, Anesthesiological and Cardiovascular Sciences, Umberto I Hospital, Sapienza University of Rome, Rome, Italy.
Summary
Prompt intervention for a stuck leaflet after transcatheter aortic valve implantation (TAVI) can prevent severe aortic regurgitation (AR) and improve patient outcomes. Early diagnosis and management are crucial for reducing complications and hospital stays.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Severe aortic regurgitation (AR) is a serious complication following transcatheter aortic valve implantation (TAVI).
- While newer valve designs reduce paravalvular regurgitation, central AR due to leaflet malfunction remains a challenge.
- Even mild AR post-TAVI can impact long-term patient outcomes.
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