Investigation of striped acoustic field modulation in microchannels based on holographic acoustofluidic chips

Accurate modulation of striped standing wave acoustic field in microchannels is of great significance for applications in biochemistry. In this work, the regulatory mechanism of the striped acoustic field in microchannels modulated by a holographic acoustofluidic chip with oblique microstructures was investigated. The effects of microstructure and acoustic wave parameters on the spacing of acoustic pressure node lines were studied. The error between the simulated and experimental results was less than 5 %. A mathematical model was established and confirmed to regulate the acoustic pressure node line spacing. The spacing of acoustic pressure node lines is found to be negatively correlated with both the inclination angle of the microstructure and the frequency of the incident wave. By selecting appropriate values for the inclination angle and frequency based on modulation effects and application requirements, a regulatory scope of approximately 55-250 μm for the acoustic pressure node line spacing can be achieved in microchannel. The model established and the conclusions drawn from this work can provide valuable guidance for particle sorting, analysis, and tissue engineering applications based on acoustofluidic chips.