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Published on: December 15, 2011
Non-tuberculous mycobacterial lymphadenitis in an infant with Hyper IgM Syndrome: A rare case report
Chunyan Zhao1, Chang Song1, Xianzhen Huang2
1Department of Tuberculosis, The Fourth People's Hospital of Nanning, Nanning, PR China; Guangxi Medical University, Nanning, PR China.
Abstract:
Hyper Immunoglobulin M syndrome is rare. We report a 7-month-old infant who suffered Hyper Immunoglobulin M syndrome and developed non-tuberculous mycobacterial (NTM) lymphadenitis. The former was confirmed by next-generation sequencing revealed X-linked recessive, whilst initial immunoglobulin testing displayed high IgM levels. The latter was diagnosed by lymph node pus acid-fast staining smear, culture and PCR. The child received therapy. Meanwhile, he was treated with immune supporting. The child was followed up for 11 months, and he progressed well.
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