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Breast mucoepidermoid carcinoma: about a case report
Imane Tazi1, Soumaya Ech-Charif1, Ismail Boujida1
1Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center, Rabat 10100, Morocco; Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Morocco.
Introduction And Importance:
Breast mucoepidermoid carcinoma (MEC) is a very rare entity and usually underdiagnosed by the pathologists.
Case Presentation:
54-year-old woman with a single palpable mass on the left breast with no nipple discharge. She underwent tumoretomy. Microscopic examination revealed a well circumstanced intracystic proliferation consisted of mucoid, epidermoid and intermediate cells. The tumor cells were positive for ER, PR but negative for HER2.
Clinical Discussion:
Salivary glands like neoplasms are described in the breast, and only represent 0.2 % to 0.3 % of breast carcinomas. They usually fall under the triple negative breast carcinomas. However some cases were described in the literature with a luminal A profile. The grading score used in the salivary glands based on the presence or lack thereof nuclear anaplasia, necrosis, high mitotic activity and perineural or lymphovascular invasion seems more appropriate in this rare entity.
Conclusions:
It is crucial for pathologists to think of this type of Breast carcinomas, especially when there is mucoid, epidermoid and intermediate cells and it does not have to fall under triple negative breast carcinomas.
