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Breast mucoepidermoid carcinoma: about a case report
Imane Tazi1, Soumaya Ech-Charif1, Ismail Boujida1
1Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center, Rabat 10100, Morocco; Faculty of Medicine and Pharmacy of Rabat, Mohamed V University, Morocco.
International Journal of Surgery Case Reports
|May 9, 2025
Summary
Breast mucoepidermoid carcinoma (MEC) is a rare breast cancer. Pathologists should consider MEC in differential diagnoses, as it may not always be triple-negative.
Area of Science:
- Oncology
- Pathology
Background:
- Breast mucoepidermoid carcinoma (MEC) is an exceptionally rare breast malignancy, often misdiagnosed.
- These tumors represent a small fraction (0.2-0.3%) of all breast carcinomas and share similarities with salivary gland neoplasms.
Observation:
- A case of a 54-year-old woman presenting with a palpable left breast mass is described.
- Microscopic examination revealed an intracystic proliferation of mucoid, epidermoid, and intermediate cells.
Findings:
- The tumor cells were positive for estrogen receptor (ER) and progesterone receptor (PR), but negative for HER2.
- This luminal A profile contrasts with the common classification of MEC as triple-negative breast carcinoma.
Implications:
- Accurate pathological diagnosis of breast MEC is critical.
- The study suggests that a grading system adapted from salivary gland tumors may be beneficial for breast MEC.
