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Invasive Corynebacterium striatum infection: A case of concurrent isolation from blood and cerebrospinal fluid

S A Rahil Pasha1, T Vidhya1, S Nagarathna1

  • 1Department of Neuro Microbiology, NIMHANS, Bangalore, India.

Indian Journal of Medical Microbiology
|May 9, 2025
PubMed

Insights

A patient with ruptured anterior communicating artery (ACOM) and anterior cerebral artery (DACA) aneurysms developed a rare Corynebacterium striatum infection. This case highlights the importance of monitoring for unusual infections post-neurosurgery.

Area of Science:

  • Neurosurgery
  • Infectious Diseases
  • Cerebrovascular Diseases

Background:

  • Subarachnoid hemorrhage (SAH) is a critical neurovascular condition often caused by ruptured intracranial aneurysms.
  • Anterior communicating artery (ACOM) and anterior cerebral artery (DACA) aneurysms are common locations for SAH.
  • Surgical intervention, such as craniotomy and aneurysm clipping, is the standard treatment for these aneurysms.

Observation:

  • A 60-year-old male presented with symptoms of SAH after a fall, confirmed by CT scan.
  • Imaging revealed ruptured ACOM and DACA aneurysms requiring surgical clipping.
  • Corynebacterium striatum was incidentally isolated from blood and cerebrospinal fluid (CSF) during hospitalization.

Findings:

  • Successful surgical clipping of both ACOM and DACA aneurysms was performed.
  • The patient experienced a rare, incidental Corynebacterium striatum infection during the hospital stay.
  • The clinical course, management, and outcomes of this specific infection were documented.

Implications:

  • This case underscores the potential for rare bacterial infections following neurosurgical procedures.
  • Early recognition and management of incidental Corynebacterium striatum are crucial in neurosurgical patients.
  • Further research into the pathogenesis and treatment of such infections in the context of cerebrovascular events is warranted.
Keywords:
Cerebrospinal fluidCorynebacterium striatumSubarachnoid hemorrhage

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