Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

27
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
27

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The role of urine derived exosome metalloproteinases as biomarkers for prostate cancer detection may be confounded by non-malignant prostatic inflammation.

Scientific reports·2025
Same author

Epstein-Barr Virus Related Mixed Cryoglobulinemic Vasculitis with Multi-System Involvement.

The American journal of medicine·2025
Same author

Gastric Neuroendocrine Tumors and Pernicious Anemia: A Case Report and Literature Review.

Cureus·2024
Same author

Interprofessional Continuous Glucose Monitoring for Underserved Adults with Type 2 Diabetes on Insulin or Secretagogues.

Innovations in pharmacy·2022

Related Experiment Video

Updated: May 12, 2025

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

140

Primary splenic angiosarcoma presenting as thrombocytopenia.

Talar Telvizian1, Alexander C May2, Obed Agyei2

  • 1Hematology and Oncology, Lankenau Medical Center, Wynnewood, Pennsylvania, USA telviziant@mlhs.org.

BMJ Case Reports
|May 9, 2025
PubMed
Summary
This summary is machine-generated.

This case highlights primary splenic angiosarcoma, a rare cancer. Early detection and prompt intervention are crucial for improving outcomes in patients with this aggressive vascular neoplasm.

Keywords:
Haematology (incl blood transfusion)OncologyPathologySplenectomy

More Related Videos

Application of Microwave Ablation in Laparoscopic Partial Splenectomy
03:49

Application of Microwave Ablation in Laparoscopic Partial Splenectomy

Published on: November 15, 2024

125
Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
04:40

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device

Published on: November 4, 2022

1.0K

Related Experiment Videos

Last Updated: May 12, 2025

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions
02:09

Application of Laparoscopic Partial Splenectomy with Total Blood Flow Occlusion in Benign Splenic Lesions

Published on: December 20, 2024

140
Application of Microwave Ablation in Laparoscopic Partial Splenectomy
03:49

Application of Microwave Ablation in Laparoscopic Partial Splenectomy

Published on: November 15, 2024

125
Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device
04:40

Bloodless Laparoscopic Partial Splenectomy Assisted by Bipolar Radiofrequency Excision Hemostatic Device

Published on: November 4, 2022

1.0K

Area of Science:

  • Oncology
  • Pathology
  • Radiology

Background:

  • Primary splenic angiosarcoma is a rare and aggressive vascular neoplasm.
  • It is associated with high rates of metastasis and poor outcomes.
  • Nonspecific symptoms often delay diagnosis.

Purpose of the Study:

  • To report a case of primary splenic angiosarcoma presenting with thrombocytopenia.
  • To emphasize the diagnostic challenges and clinical management of this rare malignancy.
  • To underscore the importance of early detection and intervention.

Main Methods:

  • A case study of a male patient in his 70s presenting with thrombocytopenia.
  • Diagnostic workup included physical examination, blood tests, imaging (including PET scan and brain MRI), and splenectomy.
  • Treatment involved surgical resection and surveillance.

Main Results:

  • Splenectomy confirmed primary splenic angiosarcoma.
  • Imaging revealed no evidence of metastasis at diagnosis.
  • The patient is currently under surveillance.

Conclusions:

  • Primary splenic angiosarcoma poses a significant clinical challenge due to its rarity, aggressive nature, and nonspecific presentation.
  • Considering rare malignancies is vital in the differential diagnosis of thrombocytopenia.
  • Early detection and prompt intervention are fundamental for improving patient outcomes.