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Tubulointerstitial nephritis and uveitis post COVID-19 infection in an adult

John Lau1, Ken-Soon Tan2

  • 1School of Medicine, The University of Queensland, Brisbane, Queensland, Australia johnlau90@gmail.com.

BMJ Case Reports
|May 9, 2025
PubMed

A woman in her 50s contracted COVID-19 and initially presented a few weeks afterwards with left eye pain and redness. She was diagnosed with uveitis and treated with glucocorticoid eye drops. Renal impairment was found on laboratory investigations performed following the diagnosis of uveitis, and urine testing showed proteinuria. Serological testing showed no cause for the new findings, and renal imaging was unremarkable. A renal biopsy was conducted and histology was consistent with tubulointerstitial nephritis. A diagnosis of tubulointerstitial nephritis with uveitis (TINU) was established, and she was given prednisolone, with resolution of proteinuria and improvement in renal function. While TINU is rare but well described in children, it can also uncommonly be a cause of renal impairment in adults post COVID-19 infection, similar to cases in children.

Keywords:
ProteinuriaSARS-CoV-2

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