Related Experiment Video
Updated: Jun 13, 2025
A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
Published on: April 24, 2020
Post-Y90 PET Dosimetry
Ali Afrasiabi1, Johannes L du Pisanie1, Bahareh Gholami1
1Department of Radiology, University of North Carolina at Chapel Hill, 101 Manning Drive, Chapel Hill, NC 27514, USA.
Abstract:
Transarterial radioembolization with yttrium-90 is widely used to treat unresectable liver cancer by delivering radiation directly to tumors. While post-treatment imaging generally relies on single-photon emission computed tomography (SPECT) and SPECT/computed tomography (CT), lower signal-to-noise ratio and spatial resolution limit its application. PET/CT and PET/MR imaging have proven to provide more effective image quality, yielding clearer images for accurate dose quantification and correlation with treatment response. PET-based imaging is crucial for refining dose-response and dose-toxicity relationships in personalized dosimetry, although its limited availability challenges its widespread use.
More Related Videos
09:55Radiosynthesis, Quality Control, and Small Animal Positron Emission Tomography Imaging of 68Ga-Labelled Nano Molecules
Published on: October 4, 2024
10:21Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
Published on: August 8, 2019
Related Concept Videos
01:29Positron Emission Tomography
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
Fundamental Principles of PET
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...