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Updated: Jun 17, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
SS-OCT-based ocular biometric characteristics of patients with nuclear cataract
Zhao Xu1, Ke Yin1, Liming Wang1
1Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, No. 251 Fukuang Road, Nankai District, Tianjin, China.
Background:
This observational, prospective, analytical, and cross-sectional study was designed to systematically analyze ocular biometric parameters in patients with nuclear cataract exhibiting nuclear hardness grade ≥ 3 according to the Emery-Little classification under slit-lamp examination who scheduled for phacoemulsification. Ocular biometric measurements were acquired using the IOL Master 700, a swept-source optical coherence tomography (SS-OCT) device.
Results:
Age was negatively correlated with axial length (AL), anterior chamber depth (ACD), white-to-white (WTW), and pupil diameter (PD) (rAL = - 0.13, rACD = - 0.26, rWTW = - 0.18, all P < 0.001; rPD = - 0.09, P < 0.01) but positively correlated with total steep keratometry (TKs) (rTKs = 0.13, P < 0.001). AL was negatively correlated with total flat keratometry (TKf), TKs, and WTW (rTKf = - 0.3, rTKs = - 0.27, rWTW = - 0.18, all P < 0.001) but positively correlated with ACD and PD (rACD = 0.43, rPD = 0.10, all P < 0.001). Men had smaller TK and PD but larger WTW than women.
Conclusions:
These findings highlight significant sex-related differences in biometric parameters among patients with nuclear cataract, which are closely related to AL and age. Considering variation with these parameters helps personalize surgical plans and prevent complications.

