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Published on: October 29, 2013
3,6-Anhydrogalactal as a Single-Addition Monomer for Chain-End Functionalization of Metathesis Polymers
Zefeng Zhou1, Quan Pham1, Gavin J Giardino1
1Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States.
None:
Controlling the structure and reactivity of the chain-end group is a central objective in modern polymer chemistry. Here we introduce 3,6-anhydrogalactal as a single-addition monomer that enables efficient and versatile chain-end functionalization of metathesis polymers. Readily synthesized from biomass-derived galactal, 3,6-anhydrogalactal exhibits excellent single-addition reactivity, allowing precise chain-end modifications even when introduced simultaneously with the propagating monomer. Theoretical calculations provide mechanistic insights into the unique reactivities governing its single-addition behavior. Its broad functional group compatibility facilitates diverse applications, including block copolymer synthesis, polymer-polymer coupling, and bioconjugation, demonstrating significant potential for advancing polymer materials and bioconjugation strategies.
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