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Polyneuropathy due to n -Hexane Intoxication - A Case Series
Khichar P Shubhakaran1, Pradeep Lalwani, Nidhi Yadav
1Department of Neurology, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India.
Abstract:
n -Hexane, a volatile organic chemical, is notorious for its neurotoxicity in occupational settings. We present four patients working in a needle manufacturing factory who presented with polyneuropathy after exposure to n -hexane by inhalation. Cerebrospinal fluid showed albuminocytological dissociation. Nerve conduction study (NCV) showed primary demyelination with secondary axonal polyneuropathy. Excluding the other possible causes, the diagnosis of n -hexane neuropathy was kept. Patients were managed with symptomatic treatment and showed marked improvement in 6-month follow-up.
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