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Optimal Analgesic Volume for Popliteal Plexus Block After Total Knee Arthroplasty: A Blinded RCT Protocol
Johan Kløvgaard Sørensen1,2, Mikkel Schjødt Heide Jensen1, Ulrik Grevstad3
1Department of Anaesthesiology, Elective Surgery Centre, Silkeborg Regional Hospital, Silkeborg, Denmark.
Acta Anaesthesiologica Scandinavica
|May 10, 2025
Summary
This study compares 10 vs. 20 mL of local anesthetic for popliteal plexus block (PPB) after total knee arthroplasty. It aims to optimize pain management and opioid use following surgery.
Area of Science:
- Anesthesiology
- Orthopedic Surgery
- Pain Management
Background:
- Popliteal plexus block (PPB) enhances multimodal analgesia after total knee arthroplasty (TKA) but optimal local anesthetic volume is unknown.
- Maintaining motor function is crucial during postoperative recovery.
- Current research seeks to define optimal PPB parameters for TKA patients.
Purpose of the Study:
- To compare the analgesic efficacy of 10 mL versus 20 mL of local anesthetic in PPB.
- To evaluate PPB as an adjunct to femoral triangle block and multimodal analgesia after TKA.
- To determine the optimal local anesthetic volume for PPB in TKA.
Main Methods:
- Blinded, controlled, randomized clinical trial with 120 TKA patients.
- Patients randomized to receive PPB with 10 mL or 20 mL bupivacaine 5 mg/mL.
- All patients received spinal anesthesia, multimodal analgesia, and femoral triangle block.
Main Results:
- Primary outcome: 24-hour postoperative opioid consumption.
- Secondary outcomes: opioid-free analgesia rates, pain intensity, muscle function, mobilization, and quality of recovery.
- Analysis will compare outcomes between the 10 mL and 20 mL PPB groups.
Conclusions:
- This trial will provide insights into the optimal local anesthetic volume for PPB.
- Findings aim to refine postoperative pain management strategies after TKA.
- Optimizing PPB volume can improve patient recovery and reduce opioid reliance.
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