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BactiVac, the Bacterial Vaccines Network.

Calman A MacLennan1, Adam F Cunningham2, Johanna E Dean2

  • 1Department of Immunology and Immunotherapy, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Jenner Institute, Nuffield Department of Medicine, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford OX3 7DQ, UK.

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Summary
This summary is machine-generated.

The Bacterial Vaccines Network (BactiVac) was established to advance bacterial vaccine development globally. It fosters collaboration and provides funding to reduce disease, death, and antimicrobial resistance.

Keywords:
Global healthInfectionOne healthPolicyTraining

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Area of Science:

  • Microbiology
  • Immunology
  • Public Health

Background:

  • Bacterial vaccines are crucial for combating antimicrobial resistance and reducing disease burden.
  • A historical lack of a dedicated network hindered progress in bacterial vaccine development and knowledge sharing.

Purpose of the Study:

  • To establish and describe the Bacterial Vaccines Network (BactiVac) and its role in advancing global bacterial vaccine development.
  • To highlight BactiVac's mission to reduce disease, death, and antimicrobial resistance through collaborative efforts.

Main Methods:

  • BactiVac unites academia, industry, policymakers, and funders from high-income countries (HICs) and low- and middle-income countries (LMICs).
  • The network supports vaccine development via Catalyst Project and Training Awards, focusing on capacity-building, especially for LMIC early-career researchers.
  • Annual meetings and partnerships facilitate information exchange, collaboration, and advocacy.

Main Results:

  • BactiVac comprises 2060 members from 92 countries, with significant representation from LMICs (51%) and industry (15%).
  • The network actively funds projects and training, addresses vaccinology bottlenecks, and promotes national and international advocacy for bacterial vaccines.

Conclusions:

  • BactiVac effectively supports and enhances the bacterial vaccinology community through financial aid and collaboration.
  • The network plays a vital role in reducing the global burden of bacterial infections and combating antimicrobial resistance.