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Introduction to Solid Supported Membrane Based Electrophysiology
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Salipro technology in membrane protein research

Siavash Mostafavi1, Tânia F Custódio1, Katharina E J Jungnickel1

  • 1Centre for Structural Systems Biology (CSSB), Notkestraße 85, 22607 Hamburg, Germany; European Molecular Biology Laboratory (EMBL) Hamburg, Notkestraße 85, 22607 Hamburg, Germany.

Current Opinion in Structural Biology
|May 11, 2025
PubMed

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Protein Diffusion in the Membrane01:24

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Proteins show rotational as well as lateral diffusion across the membrane. The lateral diffusion of proteins was confirmed through the cell fusion experiment where mouse and human cells were fused, resulting in hybrid cells. When the human and mouse cells fused, the specific membrane proteins on human and mouse cells were marked with the red and green-fluorescent markers, respectively. Initially, the red and green fluorescence was located on the respective hemisphere of the cell. As time...