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Updated: May 17, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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Factors associated with developmental delay in late preterm infants: the BRISA cohort

Paulo Ricardo Higassiaraguti Rocha1, Gabriela Pap da Silva1, Otávio Augusto Gratão1

  • 1Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Pediatria, Ribeirão Preto, SP, Brazil.

Jornal De Pediatria
|May 11, 2025
PubMed

Insights

Maternal smoking, lack of a partner, and intrauterine growth restriction are linked to developmental delays in late preterm infants. These factors are crucial for early diagnosis and intervention strategies.

Area of Science:

  • Pediatrics
  • Developmental Psychology
  • Public Health

Background:

  • Late preterm (LPT) infants (34-36 weeks gestation) are at increased risk for developmental delays.
  • Early identification of risk factors is crucial for timely intervention.

Purpose of the Study:

  • To examine sociodemographic, gestational, and birth factors associated with developmental delay in LPT infants.
  • To identify predictors for fine motor and cognitive delays in the second year of life.

Main Methods:

  • Prospective cohort study of 327 LPT infants.
  • Developmental assessment using the Bayley-III screening test.
  • Hierarchical multiple logistic regression analysis.

Main Results:

  • Maternal smoking during pregnancy correlated with fine motor and cognitive delays.
  • Living without a partner and intrauterine growth restriction were associated with fine motor delay.
  • Neonatal intensive care unit admission was linked to cognitive delay.

Conclusions:

  • Sociodemographic and perinatal factors significantly influence LPT infant development.
  • These findings inform targeted screening and intervention programs for LPT children.
Abstract

Keywords:
CognitionCohort studiesMotor skillsPremature birthRisk factors

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