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Published on: September 8, 2023
Genome-wide analyses of susceptibility genes responsible for mandibular prognathism in the Japanese population
Marie Hoshi-Numahata1, Atsuko Nakanishi-Kimura1, Haruhisa Watanabe2
1Department of Pharmacology, Faculty and Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan; Department of Orthodontics, Faculty and Graduate School of Dental Medicine, Hokkaido University, Sapporo, 060-8586, Japan.
Background:
Mandibular prognathism (MP) is a type of malocclusion characterized by an imbalance in the anteroposterior position of the upper and lower jaws. The prevalence of MP in Japan is relatively high, suggesting a unique genetic background in the population.
Highlight:
Genome-wide analyses identified susceptibility genes responsible for mandibular prognathism in the Japanese population.
Conclusion:
Identification of the genes associated with malocclusion will pave the way for personalized and precise medicine and contribute to craniofacial biology.
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