Related Experiment Video
Updated: May 13, 2025
09:54
Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
1.7K
Pregnancy Outcomes in 53 Female Lung Transplant Recipients.
Frank G Lee1, Lisa A Coscia2, Serban Constantinescu3
1Department of Surgery, Mayo Clinic, Rochester, MN.
Chest
|May 11, 2025
Summary
Planning pregnancy after lung transplantation significantly improves outcomes for both mother and child. Unplanned pregnancies in lung transplant recipients are common and linked to poorer survival rates and adverse birth outcomes.
Area of Science:
- Pulmonology
- Transplant Surgery
- Obstetrics
Background:
- Limited data exists on pregnancy outcomes for female lung transplant (LuT) recipients.
- Counseling LuT recipients on post-transplant pregnancy requires more evidence.
Purpose of the Study:
- To identify modifiable factors influencing pregnancy outcomes in female LuT recipients.
- To analyze pregnancy data in LuT recipients using the Transplant Pregnancy Registry International (TPRI).
Main Methods:
- Retrospective observational analysis of female LuT recipients.
- Data collected from the TPRI from 1991-2021.
Main Results:
- 72 pregnancies reported in 53 LuT recipients; 54% were unplanned.
- Livebirth rate was 62%, with 60% of infants born premature or low birth weight.
- Planned pregnancies correlated with higher gestational age, birth weight, and reduced risk of low birth weight.
Conclusions:
- Pregnancy after lung transplantation is achievable but carries risks.
- Planned pregnancies improve neonatal outcomes and are associated with lower post-pregnancy mortality.
- Increasing planned pregnancies is crucial for mitigating risks in LuT recipients.
