Related Experiment Video
Updated: May 13, 2025

Rodent Stereotaxic Surgery and Animal Welfare Outcome Improvements for Behavioral Neuroscience
Published on: January 30, 2012
Risk factors associated with increased mortality within 14 days of general anesthesia in specialty veterinary
Melinda R Spaar Weiss1, Jason P Hutt2, Samuel D Stewart3
1Animal Dental Center, Columbia, MD 21045, USA.
Objective:
To investigate the overall mortality rate and risk factors associated with mortality in dogs within 2 weeks of general anesthesia in a specialty veterinary dentistry and oral surgery practice.
Study Design:
Retrospective cohort study.
Animals:
A total of 3210 dogs were anesthetized for advanced imaging and/or oral surgery.
Methods:
Electronic medical records of four clinics were examined for dogs that had undergone advanced imaging and/or oral surgery requiring general anesthesia over a 2 year period (2021-2023). Data were collected on patient demographics, procedural and anesthetic details, and mortality status 2 weeks after anesthesia. Univariate analyses and multivariable logistic regression were used to identify risk factors associated with anesthetic death.
Results:
The mortality rate of the study population of dogs was 0.37%. Median age at death was statistically higher than that of dogs alive 2 weeks after anesthesia following univariate analysis (12 and 7 years, respectively). Median anesthetic duration was statistically longer in dogs that died than those that were alive following univariate analysis (177.5 minutes and 141 minutes, respectively). Following multivariate analysis, however, only older age remained a significant risk factor (odds ratio 1.364). Weight, sex, and American Society of Anesthesiologists physical status classification were not statistically significant risk factors for anesthetic death.
Conclusions And Clinical Relevance:
Data from this study may facilitate risk discussions with clients, especially owners of older dogs undergoing anesthesia in veterinary dental practices.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Inhalational Anesthetics: Overview
Local Anesthetics: Adverse Effects
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

