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Published on: September 26, 2019
[Research progress of long noncoding RNA in atopic dermatitis]
1Department of Dermatology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China. caixinying0913@126.com.
Abstract:
Long noncoding RNA (lncRNA) is a type of RNA that is longer than 200 nucleotides and does not encode proteins. Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Genetic susceptibility, damaged skin barrier and immune imbalance play important roles in its pathogenesis. Studies have shown that abnormal expression of lncRNA plays an important role in the development of many human diseases. In recent years, it has been found that various lncRNAs are abnormally expressed in AD patients and are involved in the development of AD. This paper reviews the research progress of lncRNAs in AD, aiming to provide more reference for the pathogenesis and treatment of AD.
