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Hepatobiliary Cancers in Saudi Arabia From 2000 to 2025
Khalil I Alshammari1, Ibrahim Ginawi2, Hisham Sherfi3
1Internal Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, SAU.
Cureus
|May 12, 2025
Summary
Hepatobiliary cancers, particularly liver cancer, are prevalent in Saudi Arabia. Key risk factors include viral hepatitis, smoking, obesity, and diabetes mellitus.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Hepatobiliary cancers pose a significant global health burden.
- Saudi Arabia and neighboring Gulf nations face considerable impacts from these diseases.
- Limited data exists on hepatobiliary cancers specifically within Saudi Arabia.
Purpose of the Study:
- To elucidate the epidemiology of hepatobiliary cancers in Saudi Arabia.
- To identify and clarify associated risk factors for these cancers in the region.
- To address the scarcity of comprehensive studies on hepatocellular cancers in Saudi Arabia.
Main Methods:
- Conducted a systematic electronic search of multiple databases (Medline/PubMed, Scopus, Web of Knowledge, Google Scholar).
- Utilized keywords related to hepatobiliary cancer and Saudi Arabia.
- Included studies meeting specific inclusion criteria to gather epidemiological data.
Main Results:
- Hepatobiliary cancers, especially liver cancer, show significant prevalence in Saudi Arabia.
- Identified common risk factors such as viral hepatitis, smoking, alcohol consumption, diabetes mellitus, and obesity.
- Highlighted a lack of previous studies collectively examining hepatocellular cancers in Saudi Arabia.
Conclusions:
- Hepatobiliary cancers represent a notable public health concern in Saudi Arabia.
- Established risk factors for these cancers are consistent with global trends.
- Further research is warranted to comprehensively understand and combat hepatobiliary cancers in the region.
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