Multimodal Management of Complex Congenital Heart Disease: A Case of Atrial and Ventricular Septal Defects With a

Ömer Işik1, Kardelen Kizilay2, Mehmet Dik3

  • 1Cardiology, Firat University Hospital, Elazig, TUR.

Cureus
|May 12, 2025
PubMed

Insights

This case study details a female patient with complex congenital heart disease (CHD), including atrial septal defect (ASD) and ventricular septal defect (VSD). Treatment involved surgical and percutaneous closure, demonstrating effective management of residual defects and improved cardiac function.

Area of Science:

  • Cardiology
  • Medical Case Study

Background:

  • Congenital heart disease (CHD) encompasses structural heart abnormalities present at birth, influenced by genetic and environmental factors.
  • Atrial septal defect (ASD) and ventricular septal defect (VSD) are prevalent forms of CHD, with ASD often diagnosed later in life, particularly in females.
  • Early intervention for CHD is crucial for improving patient outcomes.

Observation:

  • A female patient with CHD, including ASD, VSD, and a bifid left ventricular apex, underwent initial surgical ASD closure at age 17.
  • Eight years post-surgery, residual ASD and VSD necessitated percutaneous transcatheter closure.
  • The patient also presented with mitral valve prolapse and moderate mitral regurgitation, requiring continued monitoring.

Findings:

  • Percutaneous closure successfully addressed residual ASD and VSD, significantly reducing left-to-right shunting and right ventricular pressure.
  • Post-procedural imaging confirmed effective defect closure and improved hemodynamics.
  • Persistent mitral valve abnormalities underscore the complexity of managing CHD.

Implications:

  • This case highlights the utility of a multimodal approach, combining surgical and percutaneous techniques for complex CHD.
  • The presence of a bifid apex warrants careful evaluation for associated cardiac anomalies.
  • Long-term monitoring with advanced imaging like cardiac MRI is essential for assessing ventricular function and managing potential complications.

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