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Related Concept Videos

Epistaxis01:30

Epistaxis

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Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
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Short-Term Cardiovascular Sequelae Following In-Office Posterior Nasal Nerve Cryoablation.

Jackson King1, Lane D Squires1, Daniel Cates2

  • 1Department of Otolaryngology, Head and Neck Surgery University of California Davis California USA.

Laryngoscope Investigative Otolaryngology
|May 12, 2025
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Posterior nasal nerve (PNN) cryoablation causes more significant and longer-lasting increases in systolic blood pressure (SBP) than inferior turbinate reduction (ITR). Patients undergoing PNN cryoablation require closer post-procedure cardiovascular monitoring.

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Area of Science:

  • Cardiovascular Physiology
  • Otolaryngology
  • Minimally Invasive Procedures

Background:

  • Posterior nasal nerve (PNN) cryoablation and inferior turbinate reduction (ITR) are common in-office procedures for nasal congestion.
  • Understanding the comparative cardiovascular effects of these procedures is crucial for patient safety.

Purpose of the Study:

  • To evaluate and compare the post-procedural cardiovascular effects of PNN cryoablation versus ITR.
  • To assess changes in systolic blood pressure (SBP) and heart rate (HR) following each procedure.

Main Methods:

  • A comparative study enrolled 25 adult patients undergoing either PNN cryoablation or ITR.
  • Cardiovascular parameters (SBP, HR) and pain scores (VAS) were recorded at baseline and perioperatively.
  • Maximum changes and time to return to baseline for SBP and HR were analyzed.

Main Results:

  • PNN cryoablation resulted in a significantly greater maximum change in SBP (36.5 mmHg) compared to ITR (11 mmHg).
  • The time for SBP to return to baseline was significantly longer after PNN cryoablation (57.5 min) versus ITR (8.5 min).
  • No significant differences in heart rate changes were observed between the two groups.

Conclusions:

  • PNN cryoablation is associated with more pronounced and sustained elevations in SBP compared to ITR.
  • Healthcare providers should consider these cardiovascular effects when managing patients post-PNN cryoablation, particularly regarding monitoring protocols.