Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Increased critical stimulus duration: vulnerability or episode indicator?

K H Nuechterlein, M E Dawson

Schizophrenia Bulletin

|January 1, 1985

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Corrigendum to "Effect of treatment with paliperidone palmitate versus oral antipsychotics on frontal lobe intracortical myelin volume in participants with recent-onset schizophrenia: Magnetic resonance imaging results from the DREaM study" [Schizophr Res. 255 (2023) 195-202].

Schizophrenia research·2025

Same author

Cortical thickness, gray-white matter contrast, and intracortical myelin in first-episode schizophrenia patients treated with long-acting paliperidone palmitate versus oral antipsychotics.

Psychiatry research·2023

Same author

Effect of treatment with paliperidone palmitate versus oral antipsychotics on frontal lobe intracortical myelin volume in participants with recent-onset schizophrenia: Magnetic resonance imaging results from the DREaM study.

Schizophrenia research·2023

Same author

A combined exercise and cognitive training intervention induces fronto-cingulate cortical plasticity in first-episode psychosis patients.

Schizophrenia research·2022

Same author

MCCB cognitive profile in Spanish first episode schizophrenia patients.

Schizophrenia research·2019

Same author

Developing an international scoring system for a consensus-based social cognition measure: MSCEIT-managing emotions.

Psychological medicine·2017

Individuals with specific Minnesota Multiphasic Personality Inventory (MMPI) profiles show longer critical stimulus durations, suggesting a potential vulnerability marker for chronic schizophrenia. More demanding cognitive tasks may better identify this risk in individuals predisposed to schizophrenia.

Area of Science:

Cognitive psychology
Psychopathology
Neuroscience

Background:

The Minnesota Multiphasic Personality Inventory (MMPI) is a widely used personality assessment.
Schizophrenia is a severe mental disorder characterized by psychosis.
Schizotypal personality disorder shares some features with schizophrenia and is considered a potential risk factor.

Purpose of the Study:

To investigate whether increased critical stimulus duration is a vulnerability indicator for schizophrenia.
To compare the efficacy of different cognitive tasks in detecting deficits in individuals at risk for schizophrenia.

Main Methods:

Utilized the Merritt and Balogh letter-discrimination procedure to measure critical stimulus duration.
Compared findings with previous research using the Braff and Saccuzzo procedure.

Related Experiment Videos

Examined subjects with specific MMPI 2-7-8 profiles.

Main Results:

Nonpsychotic subjects with MMPI 2-7-8 profiles exhibited increased critical stimulus duration in the Merritt and Balogh procedure.
This procedure, with its higher processing capacity load, was more effective in detecting deficits than less demanding tasks.

Conclusions:

Increased critical stimulus duration may serve as a vulnerability indicator for a poor-prognosis, chronic form of schizophrenia.
Cognitive procedures that place a higher demand on processing capacity are more sensitive in identifying individuals at risk for schizophrenia.