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Related Experiment Videos

Positive and negative schizophrenic symptoms, attention, and information processing.

B A Cornblatt, M F Lenzenweger, R H Dworkin

    Schizophrenia Bulletin
    |January 1, 1985
    PubMed
    Summary

    Schizophrenia patients show distinct cognitive deficits. Positive symptoms link to distractibility, while negative symptoms correlate with reduced information processing capacity, suggesting independent underlying issues.

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    Area of Science:

    • Cognitive Psychology
    • Psychiatry
    • Neuroscience

    Background:

    • Schizophrenia is characterized by complex symptomatology, often categorized into positive and negative symptom clusters.
    • Attentional and information-processing deficits are frequently observed in schizophrenia, but their specific relationship to symptom subtypes requires clarification.

    Purpose of the Study:

    • To investigate the relationship between attentional deficits, information-processing capacity, and the distinct positive and negative symptom dimensions in schizophrenia.
    • To differentiate cognitive profiles of schizophrenia patients from those with depression and healthy controls.

    Main Methods:

    • Utilized a comparative design involving 16 schizophrenia patients, 17 depressed patients, and 31 normal controls.
    • Assessed participants using measures of distractibility and information processing under conditions of information overload.

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  • Quantified positive and negative symptomatology in schizophrenia patients.

    • Main Results:

    • Schizophrenia patients exhibited significantly lowered processing capacity compared to depressed patients and normal controls, indicating specificity to the disorder.
    • A positive correlation was found between positive symptoms in schizophrenia and distractibility.
    • Negative symptoms in schizophrenia were associated with reduced information processing capacity.

    Conclusions:

    • The findings support the hypothesis that positive and negative symptoms in schizophrenia may arise from independent pathological processes.
    • Cognitive deficits, specifically distractibility and processing capacity, are differentially related to symptom dimensions in schizophrenia.