Related Experiment Video
Updated: May 13, 2025

Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
Published on: October 18, 2011
Research Trends and Knowledge Atlas of Radiotherapy-Related Cognitive Impairment: A Bibliometric Analysis
Yaqian Tan1,2, Qi Song3, Siyuan Gao4
1Department of Pharmacy, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China.
Background:
Radiotherapy is one of the main therapeutic methods for tumors, and radiation- related cognitive impairment has attracted increasing attention. The purpose of this study was to explore the research prospects in the field of radiotherapy-associated cognitive decline through bibliometric analysis.
Methods:
Literature on radiotherapy-related cognitive impairment published during 2004-2023 were extracted from the Web of Science Core Collection database. VOSviewer and R-bibliometrix were utilized to perform bibliometric analysis.
Results:
A total of 8,365 publications were retrieved from the database. The United States emerged as the leading country in this research field, with St. Jude Children's Research Hospital identified as the most productive institution. Thomas E. Merchant was the most prolific author in this field, while Charles L. Limoli was the most frequently cited scholar. The research hotspots have gradually shifted from cognitive function and outcome measurement to the development of new therapy models.
Conclusion:
This study comprehensively examined the research hotspots and knowledge atlas of radiotherapy- related cognitive decline from a bibliometric perspective. Our results would assist scholars in identifying potential collaborators and significant literature in this field while also providing valuable guidance for future research directions.
More Related Videos
11:24Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy
Published on: October 18, 2011
06:20Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
Published on: March 11, 2021
Related Concept Videos
Cancer Survival Analysis
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...