[Correction of myopia with implantable collamer lenses]

This study evaluated the effectiveness of the implantable collamer lens (ICL) V4c in the surgical treatment of myopia.

The study analyzed the outcomes of ICL V4c implantation in 616 eyes with myopia. Visual acuity, refraction, intraocular pressure (IOP), anterior chamber angle (ACA), vault height, and corneal endothelial cell density (ECD) were evaluated. Patients were examined preoperatively and followed up for one year.

Preoperative uncorrected and best-corrected visual acuity were 0.04±0.02 and 0.83±0.12, respectively, improving to 0.97±0.10 and 0.97±0.10 one year postoperatively. The efficacy index was 1.17±0.17, and the safety index was 1.18±0.18. The spherical equivalent (SE) decreased from a preoperative value of -8.79±2.62 to 0.20±0.58 D at one year (p<0.0001). The ACA decreased from 39.46±4.97° preoperatively to 22.79±4.74° at one year. Vault height was 747±280 μm on the first postoperative day and 755±285 μm at one year (p<0.72), with no tendency for reduction over time. ECD was 2784±244 cells/mm² preoperatively and 2755±254 cells/mm² at one year (p<0.29).

No significant linear regression was found between IOP, vault, and ACA.

In a large cohort of patients who underwent ICL V4c implantation using the standardized technique, the procedure was demonstrated to be a highly effective, safe, and predictable refractive surgery option for correction of myopia of various degrees, and helped achieve stable visual outcomes. The decrease in spatial relationships in the anterior chamber following standard ICL V4c implantation did not lead to increased IOP.