Denitrative Iodination of Nitroarenes via Light-Promoted Reduction
Ye Wang1, Wenyan Zhao1, Dongcheng Zheng1
1Engineering Research Center of Photoenergy Utilization for Pollution Control and Carbon Reduction, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China.
Abstract:
Aryl iodides are essential synthons in organic synthesis, whose conventional preparations often suffer from poor selectivity or necessitate multistep procedures. Herein, we present a light-driven denitrative iodination as a one-step approach that directly converts nitroarenes to iodoarenes under mild and transition-metal-free conditions. This streamlined method operates in the absence of strong Brønsted acids, ensuring broad functional group tolerance, including esters, cyano groups, halides, and heterocycles, while also offering operational simplicity and scalability.
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