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Biomedical and Clinical Sciences
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Predictive and prognostic markers
Race, Ethnicity, and Tumor Genomic Testing in Prostate Cancer

Race, Ethnicity, and Tumor Genomic Testing in Prostate Cancer

Zeynep Irem Ozay ¹, Neeraj Agarwal ¹

Zeynep Irem Ozay ¹, Neeraj Agarwal ¹

¹Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City.

⁰Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City.

Jama Network Open +

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May 12, 2025

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May 12, 2025

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Summary

No abstract available on PubMed

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Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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