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Updated: May 22, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Pd-Catalyzed Photoinduced Interceptive Decarboxylative Allylation
Franz-Lucas Haut1, Filip S Meger1,2, Tomás G Santiago1
1Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology, Av. Països Catalans 16, 43007 Tarragona, Spain.
Abstract:
Herein, we describe a photoinduced Pd-catalyzed interceptive decarboxylative allylation of allyl esters. Our protocol provides a new gateway to enable atom pair swaps or a series of contractions and elongations, thus offering unconventional disconnections and a modular yet broadly applicable tool for rapidly and reliably accessing sp3 architectures in drug discovery.
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